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KMID : 1103720100630040299
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Journal of the Korean Society of Radiology
2010 Volume.63 No. 4 p.299 ~ p.306
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The Radiologic Features of Cystic versus Noncystic Glioblastoma Multiforme as Significant Prognostic Factors
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Choi Seung-Joon
Hwang Hee-Young
Kim Na-Rae
Lee Shin-Woo
Kim Jung-Ho
Choi Hye-Young
Kim Hyung-Sik
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Abstract
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Objectives:The purpose of this study was to determine the preoperative radiological characteristic and survival differences of glioblastoma multiforme (GBM) with and without cysts.
Methods: Twenty-one GBMs were collected retrospectively; these tumors were pathologic confirmed as GBM. Based on the preoperative MR imaging, we compared the cystic GBMs with the noncystic GBMs according to the the tumor size, the tumor interface, the tumor wall thickness and peritumoral edema.
Results:Seven cases were classified as cystic GBMs and fourteen were noncystic GBMs. The cystic GBMs had a well-defined tumor interface, a less than 2 cm thickness of the tumor wall and less than 40 cm3 thick peritumoral edema as compared to that of the noncystic GBMs. There was a statistically significant difference in age between the patients with cystic tumors and those with noncystic tumors. For the patients with cystic GBMs and noncystic GBMs, median survival time after surgery was 43.8 months and 12.5 months, respectively.
Conclusions: The cystic GBMs had a well-defined tumor interface, a thin wall and minimal edema, as compared with that of the noncystic GBMs. The patients with cystic GBMs were significantly younger and they had more favorable survival outcomes than did the patients with noncystic GBMs.
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KEYWORD
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Glioblastoma , Brain Neoplasms , Magnetic Resonance Imaging
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